IN THIS MONTH'S ISSUE:
Announces results of Dutasteride Study
outperforms Propecia for hair loss in clinical trial results
released this month.
folks, your patience is starting to pay off. A new
treatment which has been in the sights of many hair loss
sufferers for many months has officially proven itself more
effective than Propecia at maintaining and regrowing
hair. The Chart to the left compares Dutasteride's
hair count results (Orange Bars) to 5 times the normal
Propecia dosage, and the hair counts it returns (Green
Bar). As you can see, though the difference may seem
only marginal, Dutasteride has proven itself superior, as a
0.1mg dosage can equal 5 times the Propecia dosage in effect
on hair count.
Propecia used to hold the title as being the most effective
clinically proven hair loss treatment on the market. With an
83% maintenance rate after 2 years, it has helped millions of men
keep their hair. However, its relatively low success rate at
hair regrowth has been a major point against it. Only 5% of
users in the Propecia FDA trials saw moderate regrowth in the
Crown, and only 4% in the Vertex. Part of its lackluster
sales performance was due to the incredible patience its users
required. Sometimes taking up to 1 year to even see a
stoppage of hair loss, and nearly a year and a half for some to
see any thickening at all, many people just don't bother.
Patience is not a very common human trait. Those that stick
with it for a full year or more almost always are pleased with the
results, but those impatient types may have a new toy to play with
come the end of 2001.
last month, Glaxo announced that it had submitted an NDA (New Drug
Application) to the FDA for GI198745, also known as Dutasteride,
for use with Benign Prostatic Hyperplasia. This is the same
original use for Finasteride, the active ingredient in
Proscar. It wasn't until men started experiencing hair
growth as a side effect, did they bottle it in 1mg form and call
it Propecia. So goes the story for Dutasteride.
Method of Action
Dutasteride differs from
Propecia in that it blocks both types of the enzyme
5-Alpha Reductase, whereas Propecia blocks only one.
It is this enzyme that combines with Testosterone to
create DHT, which ultimately destroys hair. There
has been a longstanding debate as to whether blocking the
other type of enzyme will have any effect on hair
loss. Now we know.
As compared to six
months on Propecia...
Want to discuss this
Announcement with others? Join the Discussion already going
on in our Forums by Clicking
For more information on Propecia,
visit our Propecia page HERE.
of SALVARE (Hairloss Solutions Newsletter)
When you see the name "Salvare"
or receive a "Hair Loss Solutions Newsletter" in the
Many of our users have contacted us
complaining of a recent Email onslaught from a company whom they did
not request any emails from. Last month, this company
identified itself as "SALVARE", run by a Dr. Marcus
Jones, selling new hair loss
treatment touting all kinds of amazing results.
They started stealing email addresses from hair loss discussion
forums and newsgroups, and without requesting permission, added
these email addresses to their distribution list. After a close
review of the ingredients in Salvare, we exercised our duty as a site dedicated to
spreading accurate information on new treatments, and declared
this product non-efficacious for the treatment of hair loss.
In their first mailings, Salvare continued in their unethical
footsteps by using HairlossSucks's name, as well as the name of
another reputable hair loss site in their Emails, to give the
impression that we were working together with them. Both
sites immediately demanded removal.
Soon after, the emails took a new turn, and a "Newsletter" was announced called the
Solutions Newsletter". These mailings were sent using
the email address "firstname.lastname@example.org",
an obvious and blatant attempt to fool people into thinking we
were sponsoring them. Several emails were sent to the SALVARE folks at
several different email addresses requesting immediate cessation
of this unethical conduct and repeated SPAMMING of thousands of
stolen email addresses. All emails were ignored.
As emailings continued, consumers
began expressing outrage at Salvare for the abuse of their private
email addresses, and continued spamming. Dr. Jones actually
replied at one point challenging one of these consumers to meet
him in person so he could inflict physical harm on them,
commenting that they surely were weak. It was reported in
the alt.baldspot newsgroup that Dr. Jones had his medical license
revoked for use of illegal Steroids several years ago.
In the most recent newsletter, the writers of the newsletter claimed to be
completely independent from the SALVARE web site and snake oil
products. Mr. Jones must have forgotten he used to
sign the Emails himself... after well over 10
to 15 emails sent by this company, the most recent mailing sent on
Feb 27, 2001 still says at the bottom of it: "Forgive
us if you received this notice in duplicate but there was a
computer glitch that occurred during mailing. This is the
only correspondence that you will receive from us unless you
request additional information."
If you receive any mailing from
SALVARE or a "Hair Loss Solutions" newsletter, please
forward the email to email@example.com
and let them know that you are being SPAMMED, and did not request
to receive the Email. Be advised that HairlossSucks is NOT
sending these newsletters out, and do not in any way support or
promote the product known as Salvare. We have spent an
extensive amount of time evaluating their product, and found it to
be completely untested, unproven, and its ingredients *DO NOT*
live up to efficacy standards for legitimate hair loss treatments.
Steer very clear of this treatment, and do not be deceived by the
seemingly informative newsletter they're sending out.
Protein (VEGF) Grows Thicker Hair
No more comb-overs. An end to hair plugs. Rugs go back on the floor where they belong.
If an experiment in mice works in men, it may be possible to grow thicker hair, scientists in Boston said on Thursday.
They said they found a protein normally associated with blood vessel growth that makes hair follicles bigger. Just as a chimp looks hairier than a person with the same number of hair follicles because of its thicker strands of hair, balding men could be given thicker manes, the researchers said.
"In male pattern hair loss, it's not that the follicles are gone. They're just miniature follicles," Dr. Michael Detmar, associate professor of dermatology at Massachusetts General Hospital in Boston, who led the study, said in a statement.
"If anyone could find a way to make the follicles bigger, men might grow hair again."
The key, he and colleagues report in the Feb. 19 issue of the Journal of Clinical Investigation, might be a protein called VEGF now used experimentally to help people grow their own heart bypasses.
VEGF, or vascular endothelial growth factor, helps the body grow blood vessels. It can help heart disease patients and is one of the proteins blocked in certain experimental anti-cancer therapies aimed at starving out tumors.
BLOOD CIRCULATION KEY TO THICK HAIR
But as any barber will attest, blood circulation is also associated with hair growth. Some studies have tended to support this, finding that people with hair loss may have fewer blood vessels.
Detmar's team, which included dermatology researcher Kiichiro Yano, compared two groups of mice -- one "wild-type" and the other genetically bred to produce extra VEGF.
The mice with extra VEGF grew fur faster and thicker in the first two weeks of life, they found. When they were shaved at two months, they grew back fur that was 70 percent thicker than normal mice.
Blood vessels surrounding their fur follicles were also larger, the researchers reported. And when they treated normal mice with a drug that blocks VEGF, their fur grew in thin and with bald spots.
"So by modulating VEGF, we can directly influence the size of the hair," Detmar said.
They are now working on a way to get VEGF into the scalp in a cream or ointment.
"The question now is can we, by this method, improve hair growth in humans?" he said. "Applying it to humans will be the big challenge."
& After Photos!
Mike offered to let us host his
before and after photos showing the great results he is having
with Rogaine and Propecia after more than a couple years of daily
use. More proof that these treatments do indeed work!
To see his great progress, Click
For more before and after photos,
check out our Before &
After Photos Section.
For more information on Propecia, Click
Here. If you'd like to read more about Rogaine, Click
McElwee - Thoughts on VEGF
The following is a review by Kevin
J. McElwee, Ph D in Dermatology on VEGF- the subject of the
big announcement above regarding the new discovery about its
effect on hair density.
Kevin J. McElwee - Thoughts on
March 3, 2001 - Vascular Endothelial Growth Factor (VEGF) is a naturally produced chemical called a cytokine. Cytokines are a
signaling mechanisms that cells use to communicate with each other.
Cells with appropriate cytokine receptors react in specific ways when they receive a signal. As its name suggests, VEGF stimulates endothelial cells of blood vessels to proliferate and grow, a mechanism celled angiogenesis (angio=blood vessel, genesis=formation).
VEGF was originally identified in tumor biology. Tumors grow very large very rapidly and to do this they need a lot of nutrients. To ensure a good supply, tumor cells may produce VEGF to induce blood vessels in surrounding healthy tissue to grow into the tumor. VEGF production and increased angiogenesis can also bee seen in wound healing and in some diseases such as psoriasis. However, VEGF is also produced by normal, healthy cells in various organs to maintain a good blood supply.
VEGF as a stimulator of hair growth is not a new idea. Several studies looking at product expression have demonstrated VEGF production in various hair follicle compartments. Hair
follicles have a cycle of growth, called anagen and rest, telogen. When hair follicles are resting they are relatively small and inactive, but when they enter a growth phase they become much larger and the cells of growing hair follicles are the fastest proliferating non-tumor cells in the body. To enable this increased cellular activity, a good nutrient supply is required and it has been shown that as hair follicles leave telogen and enter anagen, angiogenesis is stimulated. An intricate network of blood vessels forms and surrounds hair follicles as they enter anagen.
This study is a significant step in our understanding of hair cycle control and is the first to perform functional assays on hair follicle growth under the influence of VEGF. The scientists were previously involved with examining VEGF and angiogenesis in skin tumors and other inflammatory skin diseases. For their studies, they produced a genetically mutated (transgenic) mouse that consistently over expresses VEGF in the skin. In their previous studies they noted that the skin developed a very extensive
system of blood vessels and they hypothesized that this might affect hair follicle activity.
This study examined tissues from the transgenic high VEGF expressing mice for the extent of angiogenesis around hair follicles, measured the size of the hair follicles, and compared these statistics with those from normal mice. In addition, the researchers injected an antibody that blocks VEGF activity into normal mice and also exposed cultured hair follicle cells to VEGF. They found that the transgenic mice had significantly larger anagen hair follicles in association with VEGF production and angiogenesis as
compared to normal mice. Blocking VEGF activity resulted in a delay of hair follicles switching from telogen to anagen and much smaller anagen hair follicles developed. Their culture studies showed that VEGF had no direct stimulatory effect on hair follicle growth. That is, it was the formation of blood vessels that allowed increased hair follicle activity in the mutated mice and not any direct effect on the hair follicle cells by the VEGF signal. The study concludes that VEGF has an important role in
controlling hair biology and that hair follicle size is partly dependant on VEGF induced angiogenesis.
Previously it has been suggested that impaired angiogenesis may play a role in androgenetic alopecia. However, while VEGF seems to have a significant indirect effect on hair follicles, it does not act in isolation. Many cytokines and other factors can stimulate or inhibit hair follicle activity. Whether hair follicle growth could be stimulated by injecting VEGF or the DNA coding for VEGF into skin remains to be seen. There are potential side effect risks as the angiogenesis would not be restricted to the hair follicles. There will also be other limiting factors involved including the natural production in normal skin of angiogenesis inhibiting factors. The maximum possible size of a hair follicle is probably limited by the size of the dermal papilla and an upper limit to the level of activity by these cells. Most likely then, gene therapy for hair loss could involve VEGF, but in itself this may not be enough. A cocktail of DNA coding for several genes is probably required.
~ Kevin J. McElwee
[Keratin.com is a site unique in providing information on over 50 different hair loss conditions including pattern baldness, Telogen Effluvium and Alopecia Areata. Keratin.com has an active discussion board attracting regular readers and posters as well as new information seekers]
Hair Piece inventor Tries to Kill Wife
BUFFALO, N.Y. - Anthony Pignataro, a plastic surgeon who became a TV celebrity as the creator of snap-on hairpieces, was living the good life four years ago.
A wife and children. A red Lamborghini in his driveway. Big-game hunting trips and private-school educations for the couple's son, now 13, and daughter, now 11.
But it all began to fall apart when Pignataro admitted to negligent homicide in the death of a breast surgery patient.
On Friday he will be sentenced to five to 15 years in prison for poisoning his wife with arsenic, leaving her with reduced feeling and mobility in her limbs.
Authorities said he poisoned his wife in a twisted attempt to show that sometimes people die, despite the efforts of the best doctors.
The son of a surgeon, Pignataro gained local celebrity for his 1990s invention of a hairpiece that bolts to snaps surgically implanted in the scalp. He was his own first patient and demonstrated his snap-on hair on "The Maury Povich Show," "Hard Copy" and elsewhere.
But Pignataro, who obtained his medical degree in Puerto Rico in 1985, had more than his share of professional problems. Health Department records and patient accounts document at least a half-dozen cases of surgical and other errors. Among them: damage to a patient's brain during nose surgery and profuse bleeding following two "tummy tucks."
It was the 1997 case of Sarah Smith that would be his professional downfall. The 26-year-old mother's heart stopped during cosmetic breast surgery in Pignataro's office. She slipped into a coma and died a week later.
According to prosecutor Frank Clark, attending the surgery were a nurse and a high school student-office aide - inadequate anesthesia support, state health officials determined.
To avoid a manslaughter trial, Pignataro pleaded guilty to a lesser charge of criminally negligent homicide and was sentenced to six months in prison. His medical license was revoked.
As Pignataro's career ended under the glare of television lights, Deborah Pignataro was at his side, holding his hand at the courthouse.
But the Pignataro marriage was strained. After prison, he was in and out of the couple's home, living for periods with a girlfriend, authorities said. By 1999, he was back in the house.
Investigators never determined how the former doctor administered the odorless and taste-free arsenic to his wife. The victim herself was reluctant to believe her husband could be responsible for her debilitating pain, projectile vomiting, loss of orientation and feeling.
Prosecutors suggested vindication drove Pignataro: During his wife's first hospitalization, when doctors had yet to diagnose the arsenic poisoning and suspected pancreatitis, Pignataro argued vigorously for surgery.
Medical experts said she probably would not have survived the operation.
That would show the world that sometimes patients die and even the best doctors can't stop it, prosecutors said. They were prepared to offer that argument before Pignataro pleaded guilty to attempted assault.
"I do think that somehow the Sarah Smith incident prompted him to go off on this kind of crazy thing whereas he was going to somehow be vindicated," Clark said.
Part your Hair may Matter more than you Think...
Larry Williams - "This is a headliner. I feel relieved. A hair endorsement. I believe in angels. I'm so overwhelmed. I can't wait to get off the phone. I'm calling my wife on her cell. This is special."
But seriously, Larry.
"It's been a tough month or two. My dad died Super Bowl Sunday. He had a great sense of humor and would've enjoyed this. He parted his hair on the left, too."
We may not need to hold that mayoral election after all. A leadership theory holds that only one candidate has the primary qualification.
And the new mayor of St. Petersburg is . . .
Wait a minute. How can anyone know that Williams will be mayor? The primary election won't be held until Feb. 27. And even in Florida, you can't louse up an election that hasn't happened yet.
Still, Williams may have an edge, and it has nothing to do with his personality, his politics or his positions on local issues.
It's his part. Of the nine candidates for mayor, he's the only one who parts his hair on the left.
(more stunned silence)
Okay. He also wears glasses. And he's a Virgo. How could something as mundane as the part in his hair have any bearing on an election?
This brings us to Catherine Walter and her brother John.
For the past 20 years, the Walters have been collecting data and trying to advance their theory that how we part our hair goes a long way to determining how others perceive us and how successful we'll be in life, in business -- and in politics.
The Walters contend that people who part their hair on the right emphasize the right side of their brains and tend to be sensitive, compassionate and good listeners. Those who take it to the left are generally more aggressive and assertive. Type A personalities. This idea was explored in a recent article in the New Yorker.
The Walters, who live in New York City, point out that of the 44 men who've been elected president of the United States, only three -- James Buchanan, Warren Harding and Ronald Reagan -- parted their hair on the right.
The Walters sent their findings to Al Gore last summer. As a courtesy. Gore ignored them and continued to part his hair on the right. Bad move. He lost to leftie George W. Bush.
"We did try to warn him," Catherine Walter explained by phone recently. "It's sort of sad he didn't listen."
Imagine how Gore feels. A 49-cent comb cost him the presidency.
Catherine Walter is a cultural anthropologist, and John is a nuclear physicist and mathematician. Of course, given those backgrounds, they decided to open a mirror store in Manhattan.
"John thought of the theory when he was in college," Catherine said. "He changed his part from the right to the left, and his peers immediately began treating him differently. He spent years trying to talk to people about it, and they just laughed.
"I didn't get involved until 1997, and at first, I thought, "Oh, yeah. Sure.' But I have the correct training to look into it, and I found the statistics back this up."
In 1998, she looked at photographs of every current member of Congress and the governors of all 50 states.
"It's very difficult to get into office with a right part," she said. "Right parts are about 14 percent across the board."
The part theory applies equally to men and women. Margaret Thatcher and Hillary Clinton both have left parts. "And very few women in Congress have right parts," Walter said. "You don't look at a very feminine woman and think she could lead us."
(Unless it's Sandra Bullock.)
The key here is that changing the part in your hair doesn't change you, at least not dramatically.
But it can change the way others perceive you. "It's very subtle, and it happens on a subconscious level," Walter explained. "And there are a lot of things, like your eyes, for instance, that go into the immediate assessment of a person.
"All of this happens very fast. Three seconds after we glance at someone we've just met, we've decided everything we know about them. That's a survival instinct."
What about men who are . . . follicle challenged? Or people who have no part? Or who part their hair down the middle? How do you read them? By the bumps on their head?
"If their hair isn't parted, or they don't have any, that takes that item out of the equation," Walter answered. "Having no part also presents a more balanced thought process."
So Moe Howard may have been a genius.
It's not as if the Walters aren't reaching people. In 1979, then-President Jimmy Carter switched his part from right to left after they urged him to (though he never acknowledged the connection). "A Shift at the Top: President Changes Hair Style, Triggers Speculation" read the headline in the Washington Post.
It could be easily argued that Carter accomplished more after he left office. Or maybe we just think he did.
"He has been the same person his whole life," Walter said. "It's just that we perceive him differently."
Which brings us back to Larry "Lefty" Williams.
"People are usually voting for someone they don't know personally," Walters said, "and many times, they make their choice based on what the person looks like. Or they like the name.
Based on our research, I'd have to think Larry Williams has a good chance of winning."
Before Williams supporters run out and celebrate, they may want to consider this:
The Walters also cite Superman as an example of how their theory works. In the 1978 movie starring Christopher Reeve, nerdy Clark Kent had a right part.
But Superman wore a left part. So what do Williams and his opponents say about all this?
"I've actually heard of the theory, but I really haven't seriously thought about it. I have a natural part on the right. I've tried parting it on the left, but it won't stay. But my personality is that of a left-part person. I'm a calm person by nature, but very forceful when it comes to issues I feel strongly about."
So you're a leftie trapped in a rightie's body? "Yes."
"I have a related theory. My wife's father was bald. He used to say that men who were bald in the front are the thinkers and those who were bald in the back are the lovers. If they're bald all over they think they're lovers." (Rimshot.) "I have a right part, but when I look in the mirror, it appears my hair is parted on the left."
Although Baker places no stock in the part theory, "I do buy into the theory that tall men are more successful than shorter men. That's because I'm 6 feet 7."
"I don't buy it because I don't believe in pseudo-science, mysticism or magic as a way of life. I'm comfortable with my hair parted on the right. It doesn't look as good from the other side. If someone parts their hair in the middle, does that mean they can't make up their mind?"
"Right now, my hair is parted on the right. I think there would be some folks who would disagree with the analysis (of right part people). On the other hand, that's how I perceive myself. I have to force myself to speak out loud. My natural inclination is to sit back and listen. But I've been a nurse and an attorney, and we're problem solvers. We use the left side of our brain.
"Sometimes, it's a function of whether your hair is thinning."
"I part it down the middle, but 99 percent of the time, I just don't even bother combing it. I use more of the left side of my brain. I'm a borderline psychic. I can sense things other people don't sense. I can see things in my dreams before they happen."
What he sees for himself doesn't look good. "They way I look, you wouldn't vote for me. I'm just an average person. I know I'm not going to win."
"I part it front to back. That means I'm contrary, I guess. Or that I'm afraid of the fact I'm going bald. It's a bizarre theory. I doubt there's a connection, but there could be.
"Guess who I part my hair like? Bill Clinton. I recognize the man has the morals of a snake, so I wouldn't put too much stock in the theory. I don't cheat on my wife.
"But it helps that I'm the best-looking candidate."
"I don't part it. I'm neutral. Balanced. To be honest, that's certainly characteristic of my personality. I have strong positions, but I try to analyze most themes."
"I think it might be plausible, but I think because most people are right-handed, they would naturally part their hair on the left.
I don't part my hair, but I can understand the important of appearance. What happens is initially, that's how everybody makes judgments. There's an old saying about first appearances being everything. But there's another old saying that you can't judge a book by its cover. I don't know how many of us get into trouble judging people based on appearance.
But that's what people do initially, and why it would be good to have a process so that folks could get beyond the 30-second sound bites and make judgments based on something else besides appearance."
Presentation - "The Future of Hair Loss"
Imagine: Skin grafts are taken from the healthy areas of a balding man's scalp, cloned and multiplied in a laboratory, and then re-implanted in the man's scalp. How far off is this
scenario? Join our panel of experts as they discuss what may lie ahead in the treatment of male hair loss.
- How can current medications be improved?
- What new medications are on the horizon?
- What gene therapies are currently being researched?
To see this Webcast, Please click
the following link:
Future of Hair Loss Webcast
Presentation: "Hair Loss and Diet"
are many different known causes of hair loss. Hair loss can be
caused by genetic factors, by certain illnesses, or by medications
like chemotherapy. But you may be surprised to know that your diet
can also play a big role in how much hair you lose. Join our
experts as they explain why a healthy diet is an important factor
for maintaining healthy hair.
see this Webcast, Please click the following link:
Loss and Diet Webcast
Hair Loss Q & A Article
Dr. Barry Resnik answers some of your most
frequently asked questions on Hair Loss in this informative Question and Answer
Dr. Resnik is an Assistant Clinical Professor in
the University of Miami Department of Dermatology and Cutaneous Surgery and
maintains a busy practice in adult and pediatric dermatology, cutaneous surgery,
laser surgery, hair transplant surgery, facial rejuvenation, and cosmetic
surgery. He is board-certified in dermatology by the American Board of
Check out this article here: HAIR
LOSS FREQUENTLY ASKED QUESTIONS
Presentation: "The Psychological Impact of Hair
deals with hair loss differently. Some people just take it as a
fact of life, but for a lot of people it's a source of anxiety and
depression. If hair loss is troubling you, what can you do to
overcome your emotional distress, and if treatment fails, what can
you do to prepare yourself for more hair loss? Join our experts as
they discuss the psychological affects of hair loss and how it can
see this Webcast, Please click the following link:
Psychological Impact of Hair Loss
Future of Human Evolution
Do you remember what people of the future used to look like? When science-fiction movies, television and comic books strained to portray humans of the technologically advanced future, they almost always pictured us with giant bald heads that could house our massive brains. (In a particularly memorable episode of The Outer Limits, the highly evolved David McCallum also had six fingers on each hand, the better for pushing buttons, I guess.) We would become a race of supergeniuses who somehow never invented Rogaine. Of course, there were other possibilities, too. The traveler in H. G. Wells's Time Machine went far into the future and found two divergent species: the brutish Morlocks, who lived in machine-clogged tunnels, and the beautiful, bucolic, tasty Eloi. Apparently, Wells envisioned that only New Yorkers and Swedes would survive atomic war.
These days speculation about how humans might evolve seems fallow. The characters on Star Trek, for example, look as though they could just be actors in Hollywood. Maybe this shift to a closer-to-home future represents a subtle change in the public's unconscious grasp of how evolution works (yes, yes, I know: dream on).
After all, the idea that we would grow bigger brains seems to arise from a view that evolutionary progress flows like a river: we are less hairy and generally have larger brains than our ancient ancestors did, so our descendants should carry these trends to even more of an extreme. But Darwinian evolution calls for circumstances either to favor strongly the big-brained chrome-domes or to weed out drastically us more limited fuzz-heads.
Thanks to modern technology and medicine, people have taken much more control over their differential survival. Bad eyes, weak bones and countless other ills are not the barriers that they once were, happily, a fact that somewhat lessens the reproductive premium on healthful genes. Moreover, in this mobile world, genes from all populations are constantly churning together, which works against distinct subgroups' emerging with new traits. We will certainly continue to evolve naturally in small ways, but our technology may exert the greatest influence. Which means that if we all have big bald heads someday, it's not destiny--it's a fashion statement.
RU58841 is an androgen
blocker that is applied topically rather than taken orally for
systemic action. Unlike Propecia and other antiandrogens, it is
only locally effective so it is safe for men to use without many
of the side effects otherwise seen. A recent study on balding
stumptail macqaques (the primary animal testing model for male
pattern baldness drugs) showed a very good response in the frontal
area. Those who claim to have seen photographs from the article
state that the results were quite exceptional. Unfortunately
the company that makes RU58841 is located in France so accurate
information is hard to get on the progress of approval. To the
best of our knowledge, no human trials have been done using
I need some help. I just posted this message on three forums --
I am still working on RU58841. I want to make it available to everyone. Right now, I see two ways to proceed. First, have it made by a pharmaceutical company in a country such as India. Second, set up a layer of corporations and corporate shells. Make it in the US and sell it through those corporations. Either way requires time, effort, and some money. Before I put any more effort into this, I would like to know if anyone here has direct experience or knowledge about RU58841. Have you used it, or do you personally know someone who has? And I do not mean someone on the Internet. If you have direct knowledge about RU58841, please send me an E-mail. Thank you. Herb. firstname.lastname@example.org
How about including this request so that everyone here will see it?
I have read about three persons who used RU58841, with favorable results. That is not enough to spend a lot of effort on this.
I appreciate any help you can give.
Thank you. Herb
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