hair transplant
vitamin minoxidil
Home
hair loss
Start Researching
energizer bunny
Discussion Forum
antiandrogen
Join the Chat!
revivogen
Hair Loss FAQ
flutamide
What's New?
glaxo-wellcome
Member Photos
prostate cancer
Don't Panic?
5-alpha reductase
First Steps
propecia
Hair Systems
bph
Surgical Options
spironolactone
Chat Schedule
aldactone
Chat Transcripts
progesterone
Contact Us
cyproterone acetate
Advertise
cimetidine
Links
saw palmetto
Hairloss Products
kevis

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

fabao

HairlossSucks Newsletter - January 2001

HairlossSucks Newsletter

Now serving over 1,720 subscribers!
Tell a friend about subscribing today!
Interested in Subscribing? Enter your Email Address
 
Mailing goes out only once per month
and your email address will never be
given to any third party whatsoever.
 
IN THIS MONTH'S ISSUE:

iamin New Gel Prevents Chemotherapy Hair Loss copper Study on Minoxidil Absorption
grafcyte Dutasteride - Anticipation Rising! folligen Discussion Forum - User Profiles Updated
biotin Article - Non-FDA Approved Treatments folic acid Energizer Bunny Parodies Hair Loss
pieliel Multimedia Center - Women's Transplant Video viviscal Antiandrogen Treatments for Women & Men 
aminexil Warning against Vitamin based Treatments  thymuskin Girl gives up hair for Child 
polysorbate 80 Study on Minoxidil and hair weight anticancer inc Revivogen Progress Report
retin-a Article - Explanation of Hair Loss zinc Article - Proven Treatments for Hair Loss
     

Medwatch - Gell Prevents Hair Loss due to Chemo

Gel prevents chemotherapy hair loss, study finds

WASHINGTON, Jan 4 (Reuters) - A gel that temporarily stops hair from growing prevented the baldness caused by chemotherapy treatment for cancer, at least in rats and mice, researchers said on Thursday.  If it is shown to be safe in humans it might be a way to prevent the distressing hair loss and baldness that often plagues cancer patients, the researchers, at Glaxo-Wellcome Research and Development in Research Triangle Park, North Carolina, said. 

Stephen Davis and colleagues tested the gel on newborn rats and on mice that had been given transplants of human scalp. They put the gel on and gave the animals chemotherapy. Both fur and the human hair survived the cancer drugs, they report in Friday's issue of the journal Science. 

Davis said despite the development of new, gentler cancer drugs, many people would love to have a drug to prevent hair loss while being treated. "There is still a significant unmet medical need," Davis said in a telephone interview. "There are still several agents for advanced metastatic (spreading) cancer in the breast, lung and colon that have severe side-effects, including hair loss." 

Perhaps ironically, the compound works by stopping hair growth. 

Many cancer drugs work to kill rapidly dividing cells. Tumor cells grow fast, so the approach works fairly well. But some healthy cells also grow fast, such as hair follicle cells and the cells that line the gut. This is why chemotherapy has side-effects such as nausea and making hair fall out. 

Davis and colleagues wanted to see if they could temporarily stop such cells from their rapid growth and make them effectively invisible to the cancer drugs. They targeted cyclin-dependent kinase 2, or CDK2, which is a key switch for turning on cell division. "The compound actually has two mechanisms -- one is an effect on arresting cell division. The second is actually blocking the process of cell death in cells exposed to chemotherapy," Davis said. 

He said his team was also seeing if a different formulation of the gel might work to stop the internal side-effects on bone marrow and the intestines, although this would be harder to do because a way would have to be found to stop the chemical from affecting other cells and from protecting the cancer cells. 

But when used on the scalp, very little seems to leak into the body, he said. 

And the team thinks their compound may work against cancer itself, stopping the out-of-control cell growth that makes a tumor. "It's a long process," Davis said. "We are still nowhere near in terms of showing these compounds would be safe to test in humans." 


dht

Dutasteride - Anticipation Rising!

Over the past few months, we have kept you up to date on the new treatment on it's way to BPH and Hair Loss sufferers called Dutasteride.  Similar to the roots in preventing and treating Prostate Cancer that Propecia had, Dutasteride is considered the "double whammy" approach, inhibiting both types of 5-alpha reductase enzyme whereas Propecia only inhibits one.  With its 83% success rate, Propecia has cornered the market and given millions of men hope to completely halt their hair loss.  Men are now turning their attention to this new Dual Inhibitor called Dutasteride, and have been for several months anxiously awaiting its release.

Fortunately, Glaxo Wellcome, the pharmaceutical company responsible for its creation, had enough foresight to begin trials for hair loss early on, however these trials were called off due to the merger they were undergoing.  

With the dawn of the year 2001, new hopes are being sparked for this supposed wonder drug.  Dermatological centers in Marburg Germany have notified HairlossSucks that they have been contacted by Glaxo to be one of the many sites for the final phase of alopecia trials this year.  Followups with them have revealed an extremely slow and nonresponsive Glaxo, however all are confident that eventually the trials will continue.

Of more interest to most hair loss sufferers, is the fact that clinical trials have already been 100% completed for this medication on BPH, and submission of an NDA (New Drug Application) is already underway for FDA approval.  It is this release of the product which has hair loss sufferers all over the world banding together in excitement.

Why all the excitement?  

Those who were close to the actual trials for alopecia (hair loss), have reported that the results of the trials are nothing less than astounding.  Dutasteride has been said to outperform both Propecia and Rogaine combined, and with a similar safety profile to both.  To have such a quality performance record, and to have the clinical trials to prove it, is something most people seeking answers to their hair loss never have the luxury of relying on.  Dutasteride brings both to the table, and reports are that it has performed with flying colors.

Recently an announcement was made that there was a potential generic version of Dutasteride going out on the market sometime prior to the actual release which is expected by Glaxo sometime this calendar year.  Some people did a little research and found the site which is claiming to have it available by April of 2001.  You can see the page here http://www.faitheaglepharm.com/prod.html.  

In response to this news there has been an incredible surge to acquire the treatment before its FDA approved release date.  Many men are seeking ways to gather a petition and put some pressure on this company to release it to them despite any problems they may encounter legally, while other men are cautioning against it for several reasons.

First and foremost this is a chemical.  Despite how badly we want to keep our hair, safety should be of the utmost concern to us here, above all else.  The currently completed clinical trials only cover the research which defines the appropriate dosage for BPH patients.  There is no information out there as to what dosage is necessary, safe, and optimal for young men experiencing hair loss.  Additionally, the safety profile for Propecia is still questioned on an INCREDIBLE frequency by men who take it, and men who don't, even after it having been on the market for several years.  If one thinks Propecia is a potent little pill, then Dutasteride should be handled with extreme caution.

Secondly, there are legal issues involved.  If word gets out to Glaxo that a company is planning on duplicating their patented medication and selling it "on the black market" as it were, there could be some major legal international health ramifications.  

The wise man will read this article with a new found hope for the future, and an awareness that the current treatments for hair loss - although not wonder drugs, are effective in stopping further loss in the majority of men and women.  Those of you on Propecia seeing success - even when Dutasteride comes out, there is no reason to rush to buy it.  Take what works for you now, and know that as time goes by, the safety profile will become more known, the effectiveness more well known, and that second option for you will always be there.  It's this peace of mind that most of us are truly seeking, after all.

Discuss this Dutasteride story and see what others are saying about Dutasteride in our discussion forum here:
http://www.HairlossSucks.com/cgi-bin/discus/show.cgi?144/165

alopecia

Non-FDA Approved Treatments for Hair Loss - Article

HairlossSucks Document Resource Center

See the Article:  http://www.HairlossSucks.com/hairlossdocs.htm
Section: 
"General Hair Loss Information"
Labeled: 
Sawaya - Unapproved Treatments for Hair Loss

If you already have the Adobe PDF viewer installed, you can click here: http://www.HairlossSucks.com/download/sawaya2.pdf

MARTY E SAWAYA, MD
JERRY SHAPRIO, MD

 
Title:  "Alopecia:  Unapproved Treatments or Indications" 
 
Summary of Article:
 
An in-depth analysis of several "hair loss treatments" which have not been approved by the FDA.
 
The first category is called "Off Label" prescription products to treat hair loss.  Namely Spironolactone (Aldactone) is covered, as is a very comprehensive description of Flutamide, its results in clinical trials and effects on animals, humans, the prostate, and other androgen target tissues.  Flutamide is discussed pertaining to the quality of its antiandrogenic effects.  Within this section is a discussion on
Progesterone, Cyproterone Acetate (another well known antiandrogen in Canada and Europe, but not so well known in the US), and Cimetidine.
 
The second category discussed is about those Over the Counter products that make Antiandrogen *CLAIMS* ...  some examples of the products discussed here are Saw Palmetto and the legitimacy of it in fighting hair loss.
 
Another treatment within this second category of OTC products that make Antiandrogen Claims, is Kevis.  The results of an actual clinical trial on the Kevis product are reviewed here, and the findings may surprise you.  Believe it or not, the efficacy of Fabao 101D is also covered in this article.  Some history on where it came from, what is in it, and whether there have been any trials to prove its efficacy.
 
If you have any questions or curiosities about any of the following products you may have heard about, they are reviewed here with some pretty revealing clinical study information for some of them:  Iamin (Copper), GrafCyte (For use in men who have just had hair transplants - FDA Approved), Polysorbate 80, Folligen, Amino Acids, Biotin, Folic Acid, Pieliel, Viviscal, Aminexil, and ThymuSkin.
 
Lastly, a review of the projects AntiCancer, Inc. is working on can be found in this article, including Genetic Research for Hair Loss and Hair Color.

david whiting

HairlossSucks Multimedia Center - Women's hair transplant!

Hair Transplantation for Women: A Visit to the Operating Room

If you're planning to undergo a hair transplant, or you're just curious about the procedure, here's a unique chance to view the surgery as we take you through the process step-by-step. Watch as an expert surgeon performs a micro graft on a woman suffering from hair loss, demonstrating: 

  • How the donor tissue is removed from the back of the head 
  • How the tissue is cut into smaller units for implantation 
  • How the scalp is prepared for implantation 
  • How the follicular units are implanted 

See the live streaming video in our Multimedia Center by going here:
http://HairlossSucks.healthology.com/focus_webcast.asp?f=hairloss&c=hairloss_womensurgeryvisit&live=yes

marty sawaya

Warning Against Vitamin Based Hair Loss Treatments

By Judy Packer-Tursman
Tuesday, January 2, 2001

If you're lucky enough to have hair growing from your scalp, rest assured that it is growing rapidly -- at an average rate of one millimeter every three days. If you're unlucky enough to be losing it, your expenses to treat balding could grow rapidly instead -- to around $100 a month. But even with the expensive combination drug therapy that many medical experts consider best, you're more likely to merely prevent or retard further hair loss than to regrow hair. And whatever benefits you gain from these drugs will last only for as long as you keep taking them.

Conventional practitioners insist that the vast majority of advertised products that claim to fight male-pattern baldness -- from vitamin formulas to saw palmetto to massage oils -- haven't been shown to work. Some dermatologists recommend a combination of the anti-wrinkle drug Tretinoin (sold under such brand names as Retin-A) and minoxidil, one of two drugs approved for baldness, but there is no clear evidence that this mixture is any more effective than minoxidil alone. Likewise, zinc has been tried for many kinds of hair problems but has never been proven useful. Mainstream doctors dismiss techniques such as acupuncture for the same reason, and even acupuncturists differ among themselves about whether the ancient Chinese art can benefit a balding head.

Mainstream and nontraditional clinicians agree that it's easier to address any type of hair loss early and that therapy works best if a person sticks with it for at least several months. They also note that hair loss, or alopecia, can sometimes be avoided by changing grooming practices. Excessive pulling from tight rollers, pigtails or cornrows, for example, can cause scarring on the scalp; hot oil hair treatments and chemicals used in permanent waves can also cause baldness.

Hit or Miss Drugs

Male-pattern baldness, which is typically seen as a receding hairline and/or balding at the crown, is by far the most common form of hair loss, affecting about half of men by age 50. Contrary to popular belief that baldness passes from mother to son, it's likely that multiple genes from both the mother and the father are responsible.

In men with this trait, heightened sensitivity to the male hormone DHT is believed to shorten the time it takes for hair to fall out. This sensitivity also reduces the size of the follicles from which each hair sprouts. When this occurs, the follicles produce a different sort of hair: Instead of being able to grow long and thick, strands are short and fine, similar to those on the arms and legs.

Hereditary baldness usually develops over many years. If shedding or thinning begins suddenly and progresses quickly, people should seek medical advice because this could be the sign of such conditions as thyroid disease, lupus, diabetes, a scalp fungus or an iron or zinc deficiency.

The Food and Drug Administration (FDA) approved over-the-counter minoxidil in 1996 to fight hereditary balding. Sold as Rogaine and its generic equals, this topical product is thought to enlarge the follicles. The prescription drug finasteride (Propecia), approved for baldness by the FDA in 1997, is thought to work by blocking the formation of DHT.

The two drugs are more effective in the earlier stages of baldness typically seen in younger men, and side effects for them appear minimal: Rogaine can cause scalp irritation, while Propecia in rare instances can cause loss of libido. Women may use Rogaine, but if they are of child-bearing age they should not take Propecia because it may cause birth defects.

Eight in 10 Propecia users and one-third to one-half of Rogaine users find that it prevents or slows further hair loss. But only 10 percent of Rogaine users and 30 to 40 percent of Propecia users get what can be described as "cosmetically useful regrowth" of hair. Doctors often suggest combining the drugs to (possibly) improve the odds.

More potent drugs are under development, including a treatment that blocks two of the enzymes that convert testosterone into DHT. (Propecia inhibits a single enzyme.) In one trial, this experimental formulation reportedly suppressed DHT by 82 percent, compared with a 38 percent rate achieved by Propecia.

For those who don't want to wait for improved drugs, hair transplantation is an option. Experts agree that techniques have improved from the days when unsightly plugs of hair blossomed like oases on otherwise barren patches of scalp. But they differ on whether transplants -- which move hair follicles from one part of the scalp to another -- produce a look that's natural enough to be worth the expense, which can run into the tens of thousands of dollars.

None of the treatments mentioned so far will work for alopecia areata, a type of hair loss that stems from an autoimmune disease. With this condition, hair likely will reappear spontaneously in six months to two years. Scarring alopecia may look like hereditary baldness, but early treatment with medications can cure this condition.

Women, especially after menopause, are not immune to hair loss. By age 70, roughly 50 percent of women experience some hereditary hair thinning, compared with 80 percent of men. Dermatologist Laurence Miller of Chevy Chase says the toughest part of his practice is not being able to help women in their forties "who are losing their hair and we can't find out why."

Alternatives Are Minimal

There's nothing outside Western medicine that unquestionably works for the major forms of hair loss -- and certainly there's a dearth of U.S. studies to back up the efficacy of alternatives. Acupuncture is perhaps the most promising technique, based on medical literature and practice from China and on acupuncturists' reports. But even they concede that the ancient healing art likely wouldn't work for hereditary baldness -- if they were to offer it for this purpose.

Michael Arnold, a physician and acupuncturist in Pacific Grove, Calif., says hair loss usually is incidental to a reduction in the body's core vitality, described in Chinese medicine as a "kidney deficiency." If a patient says he is tired and losing hair faster than his father did, Arnold says he would treat the hair loss with acupuncture, herbs and lifestyle counseling. But in general he wouldn't treat hereditary balding, which he says is "just a trait, part of the genes."

Yet Xiaoming Tian, a licensed acupuncturist in Bethesda who is a clinical consultant to the National Institutes of Health and a member of the White House Commission on Complementary and Alternative Medicine Policy, says acupuncture can "do a very good job" for hair loss that is related to stress.

Tian says he often uses a small hammer-like device called a "plum blossom," whose seven tiny needles lightly stimulate bald areas on the scalp to improve blood flow. He also uses needles and acupressure on acupuncture points along the body's meridians, or energy channels, and he draws from an arsenal of Chinese herbs, including black sesame.

Bryan L. Frank, president of the American Academy of Medical Acupuncture, a group of medical doctors and osteopaths, has heard reports about benefits of acupuncture for hair loss. "But in my opinion," he says, "it's always been a little suspicious."

For additional information you may wish to contact the following organizations:

  • American Academy of Family Physicians: www.familydoctor.org/handouts/081.html
  • National Alopecia Areata Foundation: www.alopeciaareata.com
  • For a free information package, "Alopecia Areata and Related Hair Disorders," write to the National Institute of Arthritis and Musculoskeletal and Skin Diseases, 1 AMS Circle, Bethesda, MD 20892-4675. Or call toll-free 877-22-NIAMS.

rogaine

Minoxidil's effect on Hair Count & Hair Weight

HairlossSucks Document Resource Center

See the Article:  http://www.HairlossSucks.com/hairlossdocs.htm
Section: 
"
Minoxidil Related"
Labeled: 
Minoxidil 2% and 5% Hair Density Study

If you already have the Adobe PDF viewer installed, you can click here: http://www.HairlossSucks.com/download/minox24.pdf

Title:  "Changes in hair weight and hair count in men with androgenetic alopecia, after application of 5%and 2% topical minoxidil, placebo, or no treatment." 
 
Summary of Article:

Three double-blind groups of 9 men applied either 2% or 5% minoxidil solution, or vehicle. The fourth group, unblinded, received no
treatment. Measurements showing the difference in hair weight and hair count were are shown in this study.

To see the entire study along with specific numbers, charts, and all pertinent information, please follow the link at the top of this message

To learn more about Minoxidil, please see our Minoxidil page at http://www.HairlossSucks.com/minoxidil.htm

dmso

Dr. David Whiting - Explanation of Hair Loss

HairlossSucks Document Resource Center

See the Article:  http://www.HairlossSucks.com/hairlossdocs.htm
Section: 
"General Hair Loss Information"
Labeled: 
Dr. David Whiting - Explanation of Hair Loss

If you already have the Adobe PDF viewer installed, you can click here: http://www.HairlossSucks.com/download/whiting.pdf

DAVID A. WHITING, MD
 
Title:  "Male Pattern Hair Loss: Current Understanding" 

Summary of Article: 

The current knowledge of normal scalp hair growth, hormonal and enzyme mediators, and the changes which occur in AGA, and which may be modulated by 5a-reductase inhibition, is summarized here. Discussion on the average # of follicles on a human scalp at birth, overview of the structure of the follicle and the definition of the phases of growth and loss it goes through... a description of what exactly happens when a hair enters its dormancy phase, and the role hormones play in hair growth. A very elaborate presentation of each hormone's role in the various hair growth sites on the body. 

This is a very helpful paper for those of you who are interested in seeing the scientific evidence regarding the differences between body hair, genital hair, beard hair, and scalp hair .... as well as what glands, hormones, and internal organs are responsible for their growth or lack of growth. The topic of which organs make use of DHT (and thus which organs may have slight responses to a lack of DHT) is also covered - which may be of interest to those of you who respond strongly to Propecia use and have reported various peculiar responses throughout your body. 

The process of follicle miniaturization found in typical hair loss patients is discussed at length, as well as the logic behind why only a minority of patients could never see a regrowth of hair, as well as some reasons why some men do not respond to 2% Minoxidil and treatments like it. 

More interestingly, a review of the current understanding of the genetic side of why and how hair loss occurs is in this document, and a discussion of the certain genetic diseases where hair loss is nonexistent. Many of us have seen the studies on the correlation between Hair Loss and other ailments like high cholesterol, heart disease, high blood pressure, etc... the validity of these correlations is also discussed. 

A discussion on men who were castrated prior to puberty never experienced hair loss, but when dosed with testosterone rapidly continued hair loss, and how men who were castrated after puberty versus before.. still lost their hair, and why. To top it off, an elaborate review of the difference between type 1 and type 2 alpha reductase and what kind of men (guys with no body hair, guys with a lot of body hair, etc) have abundances and deficiencies of each type. 

To Read more about Propecia, click here:  http://www.HairlossSucks.com/propecia.htm

salvare

Study on Minoxidil and it's Absorption 

HairlossSucks Document Resource Center

See the Article:  http://www.HairlossSucks.com/hairlossdocs.htm
Section: 
"General Hair Loss Information"
Labeled: 
Factors Affecting Minoxidil Absorption

If you already have the Adobe PDF viewer installed, you can click here: http://www.HairlossSucks.com/download/minoxethan.pdf

SHAHNAZ TATA
GORDON L. FLYNN
NORMAN D. WEINER

Title:  "Penetration of Minoxidil from Ethanol/Propylene Glycol Solutions: Effect of Application Volume and Occlusion" 

Summary of Article: 

This article goes into the effect of higher concentrations of alcohol in a minoxidil solution on absorption into the scalp. For many of you, obtaining optimal absorption is an issue of interest to you. This article is incredibly informative on this topic, so be sure not to miss it. Dr. Lee's products have upwards of 80% alcohol content, which is well over Rogaine's 30% alcohol content for absorption. This article MAY be one of the reason's why Dr. Lee found this method more effective. It certainly points in that direction.

It is important to note that the question remains as to whether higher absorption equals better effect on hair, however the general
understanding is that it does.

This is a very helpful paper for those of you who are interested in seeing the scientific evidence regarding the most effective way to optimize absorption of Minoxidil. DMSO as a vehicle is also briefly touched upon, which has been a topic of discussion with the SALVARE products recently.

To see the entire study along with specific numbers, charts, and all pertinent information, please follow the link at the top of this message

To learn more about Minoxidil, please see our Minoxidil page at http://www.HairlossSucks.com/minoxidil.htm

dr lee

Discussion Forum - User Profiles Updated

We have completed the update to the User Profile section on the Discussion forum!

You can see it by going to http://www.hairlosstalk.com/discussions/ and clicking the "Browse Profiles" link on the left.

We encourage everyone to register a profile in the forum and visit the messages section to take advantage of the daily interaction going on there between users like yourself.  Total posts has risen to over 2,758!

The User Registration has risen from 40 to over 115, with several newly filled out profiles you can browse.  Since the writing of this newsletter, user registration has risen another 20 to 135.  Don't hesitate to take advantage of this great resource.

growzan

Energizer Bunny Makes Light of Hair Loss Treatments

Recently a commercial on prime time television caused quite a stir in the world of hair loss sufferers.  Many of you may have seen the commercial created by Energizer, which is intended as a parody on hair loss products.   Dubbed "Growzan", the commercial starts out by shouting the praises of the new treatment for hair loss and looking like every other cheesy infomercial we've all seen many times before.  As they continue making lavish statements about it's incredible effectiveness, the bunny suddenly makes its way across the screen, and a surprised Growzan customer turns to see what the noise is.  The viewing audience is presented with his back, covered in thick brown dense body hair.

To supplement the commercial, the folks at Energizer even went so far as to create a web site featuring Growzan.  You can see it here: http://www.growzan.com/

Not surprisingly, some people are very angered by this commercial and are calling a boycott on Energizer.  Their reasoning behind the boycott is the disservice they feel Energizer has done to all the work people are doing to make hair loss a serious issue with a serious need for a cure.  They feel the commercial works to ruin the growing public concern for hair loss by once again making light of the condition.

While the majority of hair loss sufferers viewed the commercial with a bittersweet grin, it's all too important that a lesson be learned from this commercial.  The reason Energizer spent so much money making it is because there still is an assumption that hair loss products are a joke.  Why do they assume this?  Because so many DON'T WORK.

You may feel that those calling a boycott on Energizer are over-reacting.  Well, let's look at the bigger picture.  Its the snake oils that make people laugh at hair loss and cause those Energizer commercials to come about, because its the snake oils that don't work, that cause the frustration, that take money from people, and that eliminate people's trust in the ones that DO work.  It's because of the snake oils that the support for research, and the funding from private parties goes right down the drain.  Why?  They're embarrassed.  They're not convinced it's worth the money, and they consider it a useless investment for them.  

Ask around. The general consensus out there is that you can't do anything to stop your hair loss.  The sole reason for that mentality is the number of snake oils people have spent money on and saw Zero success with. They ruin all the work we all do to get the word out on what's good and true.  HairlossSucks has turned down several organizations who have come to us, asking to give us money to place their advertisement on our site for this very reason.

While a boycott on Energizer may be a bit much, you can help change the public's perception by not buying any hair loss product that cannot scientifically prove that its ingredients work for hair loss, or that violate the scientific understanding of what TRULY causes hair loss.  Nearly every snake oil out there has broken at least one of these rules.  Don't let yourself be deceived.  If the whole world isn't already talking about it, it probably isn't the new cure to hair loss.

snake oil

Article on Antiandrogen Treatments for Women & Men

HairlossSucks Document Resource Center

See the Article:  http://www.HairlossSucks.com/hairlossdocs.htm
Section: 
"General Hair Loss Information"
Labeled: 
Anti-Androgenetic Treatments for Women & Men

If you already have the Adobe PDF viewer installed, you can click here: http://www.HairlossSucks.com/download/sawaya3.pdf

MARTY E. SAWAYA, MD, PhD 

Title:  "Clinical Updates in Hair" 

Summary of Article: 

Interesting article discussing the biochemical advances in recent years in relation to Androgenetic Alopecia. DHEA and its nature as well as function is covered, as is Aromatase, an androgen found in the outer root sheath of the follicle that they feel may play a role in hair loss. 

An interesting correlation between female hair loss and Aromatase is covered, as it seems that it may play a role in suppressing the severity of hair loss in women. While this is an article that focuses heavily on female hair loss, there are some interesting points found in it regarding how men with deeper frontal recession are possibly more likely to be experiencing a hyperandrogen state systemically.

The most interesting thing about this article are its graphical representations of the Metabolic Pathway of Androgens in the Skin, the Conversion of DHA to DHT, the Conversion of Androgens to Estrogens, and an extremely elaborate graphical representation of the Cellular Mechanism for Androgens in Skin.

Needless to say, Spironolactone (Aldactone), Flutamide, Finasteride, and RU58841 are covered in this article as well.

Dr. Sawaya also provides a list of treatments for androgenetic alopecia which have been shown to at LEAST retard hair loss. A good resource no doubt.

To Discuss the highly debated treatment RU58841 and see what others are saying about it, check out the RU58841 thread in our discussion forum here:  http://www.HairlossSucks.com/cgi-bin/discus/show.cgi?144/359

ru58841

Girl Gives up Hair for Child

'Peter Pan' Lead Shears Tresses for Worthy Cause

Cary Charron cut Jessica Pearce's hair for her role in an upcoming production of Peter Pan. The tresses will go to Wigs for Kids.

In the name of art, Jessica Pearce cut off more than 2 feet of blond hair, and a child who needs it will get a beautiful wig. That way, Pearce said, when she takes to the stage as Peter Pan in Centerville later this month, she will look the part. "It's worth it. I really, really love this play. And it's exciting to give my hair away," she said. When Pearce first auditioned for the Rodgers Memorial Theater production, director Jim Christian made it clear he wanted the female leads in each of the two casts to have short hair. "It's an intimate venue and a wig would have looked wiggy," Christian said. 

And so Pearce, and the other Peter Pan, Maryl Dover, got haircuts. Dover will lose only a few inches, since her hair is chin-length. Pearce toyed with the idea of selling her hair to help pay for college textbooks. When she found out she would get only about $100, barely enough to pay for one book, she decided donating it was a better idea. She will send her tresses to an organization called Wigs for Kids. Based in Rocky River, Ohio, the nonprofit Wigs for Kids (www.wigsforkids.org) provides wigs for children with diseases that cause hair loss, or children who are undergoing medical treatments that cause them to lose their hair. "After I thought about selling it and then found Wigs for Kids, selling it didn't seem very nice," Pearce said. Besides that, she can't wait to fly with no hair to hinder her. 

shahnaz tata

Revivogen Progress Report

Rob is a verified user of Revivogen.  We recorded his purchase over 6 months ago, and he has been kind enough to give feedback on his progress thus far.

Revivogen Progress Report

How long on Revivogen? 6 Months
What other treatments are you using? None
What type of hair loss do you have? Receding Temples
What is your age? N/A
What kind of results have you seen? Revivogen was my first ever hair loss treatment, I noticed a year before starting that my hair was receding on either side of my temple, after washing my hair I could feel hairs coming out in my hand, so I started on Revivogen in June 2000, within a month it seemed to start working and now 6 months on my hairloss is dramatically reduced, and at the moment I would say it's holding steady! Although I cant say that I can see any re-growth at the moment.

Rob  robknight3@hotmail.com

For information on Revivogen, please see http://www.HairlossSucks.com/revivogen.htm

To discuss Revivogen in our Discussion Forum, please see:  http://www.HairlossSucks.com/cgi-bin/discus/show.cgi?27/106

gordon flynn

Proven Treatments for hair loss in Men and Women

HairlossSucks Document Resource Center

See the Article:  http://www.HairlossSucks.com/hairlossdocs.htm
Section: 
"General Hair Loss Information"
Labeled: 
Dr. Marty Sawaya on Hair Loss Treatments

If you already have the Adobe PDF viewer installed, you can click here: http://www.HairlossSucks.com/download/sawaya1.pdf

MARTY E. SAWAYA, MD, PhD 

Title:  "Novel Agents for the Treatment of Alopecia" 

Summary of Article: 

This article is an overview of all the proven, unproven, and "natural" remedies out there which are intended for treating hair loss in men and women. The proven ones are reviewed and evidence is shown regarding why they succeeded in clinical trials, the unproven ones are reviewed with discussions on why they're considered potentially helpful, and the natural treatments are discussed as far as what their creators and supports claim they do for hair loss.

An overview of the causes of hair loss as well as a comparison of Finasteride (Propecia), Dutasteride, and a third dual inhibitor which may be on the market soon, is done in graphical form. 

A comparison of hair loss in women and in men, and why certain treatments work for men but not for women, is covered. Safety profile of all mentioned treatments is also covered, with some specifics on the safety profile of Finasteride (Propecia), a discussion on the half life of finasteride in the system, the effect it has on the prostate, liver, etc. Minoxidil is also discussed in depth and its method of action as well.

5aR inhibitors, Super Oxide Dimutase's (SOD's), and Copper Peptide technology for halting hair loss is covered, as is GraftCyte, a product approved by the FDA for post-transplant hair treatment, for the health of the newly transplanted hair.

This article is very well known and written by a highly respected researcher in the hair loss research industry. Don't miss it.

norman weiner

 

 

wigsforkids
Copyright 2000 - 2002 HairlossSucks.com
All rights reserved - Site design by HairlossSucks.com
Privacy Policy

sods